Vulvar Cancer

GROINSS-V I: Sentinel Node Dissection as Sole Groin Staging in Early-Stage Vulvar Cancer

Vulvar Melanoma

Advanced Vulvar Carcinoma

GOG 205: Chemoradiation for Locally Advanced Vulvar Cancer

The combination of radiation therapy with weekly cisplatin chemotherapy is effective in achieving high complete clinical and pathological response rates with manageable toxicity for the treatment of locally-advanced vulvar carcinoma.

Early Stage Vulvar Carcinoma

GOG 173: Sentinel Lymph Node Biopsy in Vulvar Cancer

GROINS V II: Radiotherapy Versus Inguinofemoral Lymphadenectomy

Inguinofemoral radiotherapy is a safe alternative for IFL in patients with SN micrometastases, showing minimal morbidity. However, for patients with SN macrometastasis, radiotherapy alone resulted in more isolated groin recurrences compared to IFL.

GOG 279: Cisplatin, Gemcitabine, and IMRT for Locally Advanced Vulvar Carcinoma

Weekly Cisplatin and Gemcitabine concurrent with IMRT improved CPR in women with locally advanced vulvar squamous cell carcinoma not amenable to surgical resection.

Management of Vulvar Sentinel Lymph Nodes

Management of Vulvar Cancer Sentinel Lymph Nodes Scenarios

Vulvar Cancer Groin Management

Three clinical scenarios highlighting management strategies for vulvar cancer and the groin.