Publications Update # 57
Drug shortages, RUBY/GY018 decision aid, TOTEM trial and cancer statistics
Shitanshu Uppal
TOTEM Trial: Intensive vs. Minimalist Follow-up in Endometrial Cancer
An intensive follow-up in patients treated for endometrial cancer does not improve overall survival or relapse detection significantly compared to a minimalist approach.
Adjuvant Treatment of Endometrial Cancer - Part 1
GOG 122: Whole-Abdominal Irradiation Versus Doxorubicin and Cisplatin Chemotherapy in Advanced Endometrial Carcinoma
AP chemotherapy significantly improved both progression-free and overall survival compared to WAI in patients with advanced endometrial carcinoma, although it was associated with greater acute toxicity.
PORTEC 1: EBRT vs. Observation in Endometrial Cancer
While postoperative radiotherapy reduces locoregional recurrence, it does not impact overall survival and increases treatment-related morbidity.
GOG-99 (Keys): Adjuvant Pelvic RT in Intermediate-Risk Endometrial Cancer
Surgical Considerations in Endometrial Cancer: Part 2
Surgical considerations in the management of stage 2 and advanced-stage endometrial cancer .
Publications Update # 56
Financial planning checklist, MITO-23 clinical trial, reducing surgical site infections by using a wound protector and reducing hernia rates using small-bite closure
MITO 23
Trabectedin did not improve median OS and demonstrated a worse safety profile compared to physician’s choice chemotherapy.