Surgical Considerations in Endometrial Cancer: Part 2
Surgical considerations in the management of stage 2 and advanced-stage endometrial cancer .
Shitanshu Uppal
Publications Update # 56
Financial planning checklist, MITO-23 clinical trial, reducing surgical site infections by using a wound protector and reducing hernia rates using small-bite closure
MITO 23
Trabectedin did not improve median OS and demonstrated a worse safety profile compared to physician’s choice chemotherapy.
Surgical Considerations in Endometrial Cancer - Part 1
FIRES Trial: Sentinel LND in Endometrial Cancer
SENTOR Trial: Sentinel LND in High-Grade Endometrial Cancer
SLNB is a viable option for the surgical staging of endometrial cancer, demonstrating high diagnostic accuracy and sensitivity with minimal false negatives.
LACE trial: Laparoscopy vs. Open for Endometrial Cancer
Among women with stage I endometrial cancer, TLH is equivalent to TAH in terms of disease-free survival, supporting the use of laparoscopic surgery.
GOG 33: Surgical Pathologic Spread Patterns of Endometrial Cancer
Surgical pathology effectively identifies prognostic factors and spread patterns in Stage I endometrial carcinoma, supporting individualized postoperative therapy based on pathologic findings.
CheckMate 358: Nivolumab with or without Ipilimumab in Recurrent/Metastatic Cervical Cancer
Nivolumab alone or in combination with ipilimumab shows promise in recurrent or metastatic cervical cancer, with significant objective response rates and manageable safety profiles.
Publications Update # 55
Molecular testing in endometrial cancer. Checkmate 358 trial cervical cancer