Shitanshu Uppal

Ovarian Cancer - NACT vs. PDS

Publications Update # 65

GoodFellas reposted, all things ostomy and sentinel nodes in cervical cancer

CHORUS Trial: PDS vs. NACT

Primary chemotherapy followed by delayed surgery is non-inferior to primary surgery followed by chemotherapy in women with advanced ovarian cancer, with reduced surgical morbidity and mortality.

Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer: EORTC Trial

Neoadjuvant chemotherapy followed by interval debulking surgery is not inferior to primary debulking surgery followed by chemotherapy in patients with bulky stage IIIC or IV ovarian carcinoma. Complete resection of all macroscopic disease remains the objective in cytoreductive surgery.

Early Stage Ovarian Cancer Trials List

Early Stage Ovarian Cancer

ACTION Trial - Early Stage Ovarian 10 year

Completeness of surgical staging is a significant prognostic factor, with better outcomes observed in optimally staged patients. Adjuvant chemotherapy benefits appear restricted to nonoptimally staged patients.

Publications Update # 64

Paperpile to organize you, surgery and climate change, strategies to reduce surgical site infections, ASCO recommendations for management of cancer related fatigue and folate receptor in low grade ovarian cancer

Advanced/Recurrent/Metastatic Cervical Cancer

Tisotumab in Cervical Cancer: InnovaTV 204/ GOG-3023/ENGOT-cx6 Phase 2 trial

Tisotumab vedotin showed clinically meaningful and durable antitumor activity with a manageable and tolerable safety profile in women with previously treated recurrent or metastatic cervical cancer.