Shitanshu Uppal

Total Parenteral Nutrition

Video discussion of basics of TPN and two additional detailed TPN videos

Publications Update # 111

In praise of bullshit, ADC list and the payloads discussion, New ESTRO-ESGO-ESP 2025 endometrial guidelines, role of stents during radical hysterectomy and RAMP-201 study summary.

RAMP-201

Avutometinib 3.2 mg BIW + defactinib 200 mg BID (3-weeks-on/1-week-off) produced clinically meaningful and durable responses with manageable toxicity in recurrent LGSOC

Special July/August Edition

New Academic Year Long-term readers of this newsletter know I

Publications Update # 110

"When Death Came to Visit," a poem by Andrea Gibson, BRCA and STIC pathology, Diverting loop ileostomy in ovarian cancer, endometrial cancer conversion rates for robotic surgery, and cancer management guidelines in pregnancy.

Publications Update # 109

Everyones the hero of their own story, management of contralateral groin in vulvar cancer (with video), non-myoinvasive uterine papillary serous carcinoma with positive washings.

Publications Update # 108

An article on insomnia, question of the week (C. Diff testing), fertility preservation outcomes in CAH/G1EC, immunotherapy in transplant patients, and FDA review of PARP inhibitors.

Publications Update # 107

A discussion on how to cure loneliness in the US, Phase 2 trial - Most Circuit - Ipi/Nivo in clear cell cancer, camrelizumab and Famitinb in cervical cancer, impact of prior radiation on immunotherapy drugs, and HRT in young patients.

Camrelizumab and Famitinib in Cervical Cancer - Phase 2 Trial

Camrelizumab plus famitinib significantly improves response rate and survival outcomes compared to camrelizumab alone or chemotherapy in pretreated R/M CC with a manageable safety profile.

Publications Update # 106

MAPK/FAK Clamp - RAMP 201 Avutomentinib and Defactinib in Low Grade Ovarian, IP chemotherapy question, ROSELLA Trial and PROFECTA-II Trial, Palliative Oophorectomy in gastric cancers