PORTEC 1: EBRT vs. Observation in Endometrial Cancer
While postoperative radiotherapy reduces locoregional recurrence, it does not impact overall survival and increases treatment-related morbidity.
Shitanshu Uppal
GOG 99: Surgery With or Without EBRT in Intermediate Risk Endometrial Adenocarcinoma
Surgical Considerations in Endometrial Cancer: Part 2
Surgical considerations in the management of stage 2 and advanced-stage endometrial cancer .
Publications Update # 56
Financial planning checklist, MITO-23 clinical trial, reducing surgical site infections by using a wound protector and reducing hernia rates using small-bite closure
MITO 23
Trabectedin did not improve median OS and demonstrated a worse safety profile compared to physician’s choice chemotherapy.
Surgical Considerations in Endometrial Cancer - Part 1
FIRES Trial: Sentinel LND in Endometrial Cancer
SENTOR Trial: Sentinel LND in High-Grade Endometrial Cancer
SLNB is a viable option for the surgical staging of endometrial cancer, demonstrating high diagnostic accuracy and sensitivity with minimal false negatives.
LACE trial: Laparoscopy vs. Open for Endometrial Cancer
Among women with stage I endometrial cancer, TLH is equivalent to TAH in terms of disease-free survival, supporting the use of laparoscopic surgery.
GOG 33: Surgical Pathologic Spread Patterns of Endometrial Cancer
Surgical pathology effectively identifies prognostic factors and spread patterns in Stage I endometrial carcinoma, supporting individualized postoperative therapy based on pathologic findings.