Shitanshu Uppal
ACTION Trial - Early Stage Ovarian 10 year
Completeness of surgical staging is a significant prognostic factor, with better outcomes observed in optimally staged patients. Adjuvant chemotherapy benefits appear restricted to nonoptimally staged patients.
Publications Update # 64
Paperpile to organize you, surgery and climate change, strategies to reduce surgical site infections, ASCO recommendations for management of cancer related fatigue and folate receptor in low grade ovarian cancer
Advanced/Recurrent/Metastatic Cervical Cancer
Tisotumab in Cervical Cancer: InnovaTV 204/ GOG-3023/ENGOT-cx6 Phase 2 trial
Tisotumab vedotin showed clinically meaningful and durable antitumor activity with a manageable and tolerable safety profile in women with previously treated recurrent or metastatic cervical cancer.
Publications Update # 63
How to deal with a micromanager boss, open vs simple hysterectomy for early cervical cancer, GLP1 inhibitors in sleep apnea treatment, irrigation to reduce SSI in surgical incisions.
GOG 240: Bevacizumab in Advanced Cervical Cancer
The addition of bevacizumab to combination chemotherapy in patients with recurrent, persistent, or metastatic cervical cancer improved median overall survival by 3.7 months and was associated with higher response rates.
Locally Advanced Cervical Cancer - Part 2
Tata Memorial Hospital Trial: Neoadjuvant Chemo + Surgery vs. ChemoRT
Cisplatin-based concomitant chemoradiation resulted in superior DFS compared to neoadjuvant chemotherapy followed by radical surgery in patients with locally advanced cervical cancer.
Publications Update # 62
To Love is to be Brave by Kelly Corrigan, deep dive into PD-1 vs PD-L1 drugs and recent trials, lymph node dissection in ovarian cancer