GOG 92

A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: a gynecologic oncology group study

Date of Publication:

May 1, 1999

Pubmed Link:

Does the addition of EBRT after a radical hysterectomy improve PFS in women with stage IB cervical cancer?

Control Arm(s):

radical hysterectomypelvic lymphadenectomy

Experimental Arm(s):

radical hysterectomypelvic lymphadenectomyEBRT 4600 - 5040cGy

Primary End Point:


Inclusion Criteria:

stage IB cervical cancersquamous, adenosquamous, adenocarcinomamet Sedlis criteria

Exclusion Criteria:

abnomal KUB


rad hyst only (n=140) vs rad hyst/RT (n=137):grade 3/4 adverse events: 2% vs 7%median f/u: 5 yrsrecurrence: 28% vs 15% (SS)2yr PFS: 88% vs 97%death: 21% vs 13%


Addition of pelvic EBRT after radical hysterectomy reduces recurrences in women with stage IB cervical cancer

Olga T Filippova