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GOG 36

Positive groin lymph nodes in superficial squamous cell vulvar cancer
Date of Publication:

February 3, 1986

Pubmed Link:
https://pubmed.ncbi.nlm.nih.gov/3578430/
Hypothesis:
A low-risk group suitable for conservative surgery exists in patients with vulvar cancer.
Control Arm(s):
NA
Experimental Arm(s):
NA
Primary End Point:
Histologically positive groin nodes
Inclusion Criteria:
Prospecitive group of vulvar cancer patients who were treated by radical vulvectomy and bilateral groin node dissection from 1977 to 1984 whose tumor size was noted to be superficial,
Exclusion Criteria:
Tumor size > 5mm
Results:
272 women with tumor
Conclusions:

The lowest risk for lymph node metastases (0 observed, 2% expected) is a subset of patients with no clinically suspicious nodes, no LVSI, non-midline tumors that were either grade 1 (1-5mm thick) or grade 2 (1-2mm thick).

Reviewer:
Laurel K Berry